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For example, cultured astrocytes subjected to oxygen and glucose deprivation showed a decrease in mitochondrial membrane potential, possibly caused by the mitochondrial permeability transition pore (mtPTP) opening, which leads to a loss of intramitochondrial contents, mitochondrial respiration and ATP production [48]

The presence of TrxR1-hTrx1 complex and hTrx1 homodimer in the reaction mixture was confirmed by non-reducing SDS-PAGE (Figures 4A, B), on which the molecular weight of sulfenylhydrazine was expected to be similar to that of hTrx1 monomer

The inhibition of NMDA receptors reduces the release of substance P by neuronal cells, protecting organisms against oxidative stress [56]

Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling