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While certain senolytic compounds have shown specificity for senescent cells in preclinical models, achieving this selectivity in humans remains a significant hurdle.120 For example, some senescence-associated proteins (eg, BCL-2, p53, SASP factors) are also expressed in normal, proliferating cells, leading to potential off-target effects.31 Therefore, optimizing senolytic agents to minimize side effects while maintaining efficacy is crucial

Direct Riboflavin Biomarkers Few studies have directly assessed riboflavin status by measuring its levels in plasma and erythrocytes

A peptide might tell your pituitary gland to release more growth hormone, or signal skin cells to produce more collagen

Malinda KM, Sidhu GS, Mani H, et al