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This study will also have useful clinical implications in reducing the gut microbiota caused variation in the drug response among different populations

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Systematic Review: the Epidemiology and Natural History of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis in Adults

In cellular membranes, cholesterol in excess of the stoichiometric requirement can escape back into the cell, where it may serve as a feedback signal to down-regulate cholesterol accumulation, while some is converted to the relatively inert storage state, cholesterol esters (see below), and some is used for steroidogenesis
