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The big difference here is that cancer research, for example, deals with end of life situations, and any such research can take on higher risks than when dealing with perfectly healthy subjects

L.BianchiR.et al (2011)
Key RTKs in eye include VEGF receptors (VEGFR1, VEGFR2, VEGFR3) regulating angiogenesis, FGF receptors (FGFR1-4) controlling cell proliferation and differentiation, EGF receptor family supporting epithelial cell growth, PDGF receptors modulating pericyte recruitment and vessel stabilization
