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Description
Some data suggests that the area accessible to G-proteins on the receptor is insufficient for transduction of the receptor signal to the relatively large trimeric G-protein complex (Park et al., 2004)
Similar results were found in naturally aged mice 35
Corticotroph and melanotroph-specific transcription of POMC appears to be dependent on a CANNTG element motif synergistically binding corticotroph upstream transcription element-binding (CUTE) proteins (7)
Nutrient availability is the major regulator of life and reproduction, and a complex cell signaling network monitors the cellular energy metabolism, especially the mitochondrial ATP synthesis and NAD + /NADH ratio, are major sensors of metabolic state
