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See these diagrams: Source: Clinical Procedures for Safer Patient Care by Doyle & McCutcheon

doi: 10.1038/s41586-020-1975-8 135 OhtsuT.HarumaK.IdeY.TakagiA

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation
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