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The compound's design as a competitive inhibitor fused with HIV-TAT for cellular uptake represents advanced peptide engineering that enables intracellular delivery and specific protein-protein interaction disruption, providing researchers with tools for studying senescence mechanisms that were previously inaccessible

From lead to market: chemical approaches to transform peptides into therapeutics

Visit megaphone.fm/adchoices Essentials: The Science & Treatment of Obsessive Compulsive Disorder (OCD)In this Huberman Lab Essentials episode, I explain the biology and psychology of obsessive-compulsive disorder (OCD) and describe the neural circuitry behind repetitive "thought-action loops," including why compulsive actions actually strengthen the underlying obsessions rather than relieve them

The gene expressions and/or activities related to liver injury, lipid metabolism and oxidation, such as ACC, PPAR-, CHOP and Caspase-3, were assessed by real time PCR and western blot