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In eighteen relevant perioperative NAC meta-analyses, nine investigated the effect of NAC on renal function in cardiac surgery as the primary objective [33,35,37,38,41,44,47,48,66], three discussed general NAC use in cardiac surgery with frequent mention of renal outcomes [40,45,49], and two focused on renal outcomes in noncardiac surgery [43,46]

Reference Matuz-Mares D, Riveros-Rosas H, Vilchis-Landeros MM, Vzquez-Meza H

The susceptibility to these effects can vary among animals based on factors, such as age, sex, health condition, and method of dose administration

A 2009 paper in the Journal of Pharmacology and Experimental Therapeutics characterised that ipamorelin restored gastric motility in a rodent postoperative-ileus model (PMID 19289567)