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In this review, we discuss the growing epidemiological evidence associating these two diseases, the key factors behind immunopathogenesis, how hormone replacing therapy impacts liver function, which of the newest therapeutic targets are being researched, and mostly, we hope to raise awareness among clinicians about the possible liver impairment in endocrine pathologies as well as the need for the evaluation of thyroid function in NAFLD/NASH patients for better management and outcome [24]

Fhraeus L, Larsson-Cohn U, Wallentin L

The pleiotropy of effects spans mechanisms that alter myocyte Ca 2+ , Na + , and K + -handling (Figure 3)
