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, O 2 and H 2 O 2 ) are capable of either oxidizing or reducing other molecules depending on the standard redox potential (E) of two reactants (Table 1) (89)
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An increase in the expression and activation of histone deacetylase 2 (HDAC2) inhibits MnSOD expression by reducing the acetylation levels at histone 3 lysine 9 (H3K9) and H3K27, thereby inducing oxidative stress and apoptosis in ECs under diabetic conditions [101]
doi: 10.3389/fphys.2020.00396 108 KleiTRMeindertsSMvan den BergTKvan BruggenR
