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Description
We found a marked reduction in the mitochondrial cytochrome c oxidase enzymatic activity in rats that chronically exposed to SN

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As a result, the difference in redox potential has been exploited by researchers to create stimuli-sensitive NPs

Along with increased CYP2E1 activity there is an induction of microsomal enzymes involved in lipoprotein production, resulting in hyperlipemia which contributes to the development of MAFLD and MASH (discussed in more detail below)
