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119,120,121,122 The canonical Wnt signalling pathway affects the proliferation and differentiation of mesenchymal stem cells (MSCs) and osteoblast progenitor cells, as well as the bone resorption of osteoclasts, contributing to bone formation and playing an indispensable role in the maintenance of bone homeostasis
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Chairs Summation Prof Thci concluded by discussing the future research needed regarding the broad effects of fumarates in psoriasis and how both this class of drugs and IL-23 inhibitors should be considered for use in long-term therapy.
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