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siRNA and plasmid transfection For siRNA transfection, cells were transiently transfected with target-specific siRNA oligonucleotides (GenePharma) using the JetPRIME transfection reagent (Polyplus, Bas-Rhin, France) in accordance with the manufacturers protocol, and downstream assays were performed 48 h post-transfection

Additionally, increased frequencies of diabetes mellitus, high blood pressure, kidney pathologies, coronary artery disease and raised serum lipids were identified [20]

MPV17 -relatedmitochondrial DNA maintenance defect: new cases and review of clinical, biochemical, andmolecular aspects

In addition, the cognitive abilities of persons afflicted with certain genetic predispositions to cognitive dysfunction may also be increased, e.g
