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5,121 No studies have reported quantitatively on the benefit of sleep disorder management in populations with psychiatric conditions, but given the high psychosocial burden of idiopathic hypersomnia, it can be hypothesized that effective management of idiopathic hypersomnia (eg, improved functioning, daytime sleepiness, or sleep inertia) may positively impact psychiatric symptoms either directly or indirectly

Inflammatory stimuli cause the release of cytokines such as interleukin (IL-1), IL-6, and tumor necrosis factor-a (tnf-a), which increase the synthesis and release of CRP [156]