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ACSL4 inhibitors have decreased ferroptosis in AD mice, but their poor target selectivity makes them unsuitable for human trials (Jia et al., 2023

In summary, while small observational uses of alpha-lipoic acid in pregnancy have not reported acute problems, the absence of comprehensive safety data means ALA is not routinely recommended for pregnant or lactating women

F., Medeiros, M

Because these intrinsic test characteristics are independent of disease prevalence , the 10% rate remains constant when applied to the new population
