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Notably, this suggests that the hematopoietic response to folic acid in pernicious anemia would not occur if folic acid had been converted to 5-methylTHF in the process of intestinal absorption

But if you have low vitamin B12 levels, youll likely need to get more into your system with your doctors help

This includes: Patients with malabsorption issues due to gastrointestinal disorders Individuals with pernicious anemia or other conditions that impair B12 absorption Cases where a rapid increase in B12 levels is necessary In these cases, IV delivery gets B12 straight into the blood

Precision for convenience, or convenience for a bit less precision