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Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases

Phase I metabolism of Dkhexa was investigated using pooled rat liver microsomes

Mechanism of Action GHK-Cu exhibits a multifaceted mechanism, influencing gene expression, cellular signaling, and copper homeostasis: 2.1 Collagen and ECM Stimulation: GHK-Cu upregulates genes for collagen (types I, III, IV, VII), elastin, and glycosaminoglycans (GAGs) by modulating transcription factors like SP1 and TGF-