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In the lung, however, its ability to mitigate epithelial cell injury and its consequent signaling to fibroblasts may be of paramount importance

Cathepsin B (CTSB), a lysosomal cysteine protease released by contracting muscle, crosses the BBB and accumulates in the hippocampus and prefrontal cortex, supporting neurogenesis and cognitive function [123]
Effects of High Intensity Exercise on Oxidative Stress and Antioxidant Status in Untrained Humans: A Systematic Review
Although, evidences to support the roles of antioxidants on hormonal regulations are available, however, it may require a chronic administration in order to appreciate the modulatory roles of CGV in this process