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For TG analysis, total liver samples were extracted with chilled water-methanol-chloroform mixture (3:4:8) containing LPC (19:0) and chlorpropamide as internal standards

Potential Side Effects Most patients tolerate the GLP-1well, but some may experience mild side effects, including: Nausea Vomiting Diarrhea or constipation Fatigue These symptoms are typically temporary and improve as the body adapts to the medication

Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage