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D., Refsum, H., Bottiglieri, T., Fenech, M., Hooshmand, B., McCaddon, A., Miller, J
Adamzik K, McAleer MA, Kirby B

These two results were significantly correlated, and the authors concluded that oxidative stress is an early event in the progression of kidney disease (Gazdkov 2001)
Thus, the impact of B12 supplementation on skeletal muscle mitochondrial biology was examined in (i) aged female mice, given 12 weeks of B12 supplementation (SUPP) or vehicle control, and (ii) in human primary myotubes