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306 Studies have also confirmed that the aminosalicylic acid preparation mesalazine inhibits the levels of proinflammatory cytokines such as TNF- and IL-13 through the IL-6/STAT3 signaling pathway, restoring normal levels of ZO-1 and IL-10 in the colon and improving UC progression in rats

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Fragment 176-191 is used in in vitro research examining adipocyte biology and lipid metabolism regulation at the cellular level, including interactions with beta-3 adrenergic receptor-related signalling pathways in adipocyte cell line models and effects on intracellular lipid mobilisation mechanisms

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