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Description
Ketamine (Ketalar) is a drug with wide ranging effects on the central nervous system due to its inhibition of glutamate receptors, known as N-methyl-D-aspartate (NMDA) receptors, in the brain
Neither is FDA-approved for human use
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Upon activation, NLRP3 assembles the inflammasome, activates caspase-1, and promotes the release of interleukin-1 (IL-1) and interleukin-18 (IL-18) [174,175]
