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Description
Heme deficiency activates HRI, which phosphorylates eIF2, thereby inhibiting translation of globin mRNAs
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Figure 4 Figure 5 To test whether the reduction kinetics of roGFP2-iL is affected by GRX, roGFP2-iL was fused to the C-terminus of Hs GRX1 and the catalytic efficiency for the reduction of the resulting fusion protein by GSH was compared to free roGFP2-iL in in vitro experiments (Figure 6)
