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Perrott J, et al
Investigations into ovarian cancer metastasis and chemoresistance reveal that PRPF6 induces alternative splicing of SNHG16 (downregulating SNHG16-L while upregulating SNHG16-S), where SNHG16-L inhibits GATA3 transcription through CEBPB binding, forming a PRPF6/SNHG16-L/CEBPB/GATA3 regulatory axisa finding strongly correlated with PRPF6 overexpression in chemoresistant ovarian cancer tissues [114]
2021;14:e202000219
Orloff, M
