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Iwanaga J, Shiromoto K, Kato T, Tanaka T, Ibaragi S, Tubbs RS
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13 Additionally, lactylation of TFEB at lysine 91 in tissues of PDA patients prevents its interaction with the E3 ubiquitin ligase WWP2, reducing TFEB ubiquitination and degradation, and thereby increasing its activity and autophagy flux, contributing to pancreatic cancer
