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Zarnowski R, Noll A, Chevrette MG, Sanchez H, Jones R, Anhalt H, Fossen J, Jaromin A, Currie C, Nett JE

The higher fluid pressure in tumor tissues severely hinders the diffusion of NPs in vascular endothelial cells and deep tumor regions and results in inefficient drug delivery owing to the barrier formed by the overproduced extracellular matrix [225]

Calcium homeostasis and modulation of synaptic plasticity in the aged brain

In multiple mouse models, reducing dietary methionine inhibited tumor growth and boosted antitumor immunity by increasing the quantity and cytotoxicity of tumor-infiltrating CD8 + T cells
