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The safety conversation is further complicated by the state of the literature itself

Gut and inflammation: Individuals with persistent digestive discomfort where gut barrier support is clinically relevant, people with suspected gut-inflammation overlap contributing to fatigue or poor systemic recovery, and those with a history of NSAID-related gut irritation

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The cells would be cycling between inhibited and uninhibited states, muddying the data and making it nearly impossible to draw clear conclusions
