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Thumb Extension to Flexion Move your thumb away from your fingers and across your palm as far as you can go without pain and provided you feel no more than a mild to moderate stretch as demonstrated (figure 3)

Figure 22

Mechanism: Stimulates cell proliferation and survival Promotes anagen phase entry and extension Enhances protein synthesis Hair follicles have IGF-1 receptors that respond to stimulation Application: Subcutaneous injection Dosing: 40-80mcg per day, 4-6 week cycles Requires cycling (not continuous use) Timeline: Hair improvements visible 6-8 weeks into cycle

If your tirzepatide has been stored in the refrigerator, take it out 15 to 20 minutes before injecting