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In the case of nitrogen, this effect is partly driven by the increased demand in glutamate to sustain photorespiratory metabolism due to both the direct involvement of 2-oxoglutarate/glutamate cycling and the slight incompleteness of glycine-to-serine production, which must be compensated for by an increased N assimilation 37

doi: 10.1096/fsb2fasebj.12.1.57 162 GruenMLHaoMPistonDWHastyAH

Instead, it appears to influence multiple brain systems involved in sleep regulation and stress