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Description
A study comparing existing anti-SaCas9 and anti-SpCas9 antibodies in serum and vitreous fluid from 13 patients who underwent vitrectomy surgery found that all three serum samples tested positive for SaCas9 and SpCas9, whereas only two vitreous fluid samples were positive for SaCas9, and two others for SpCas9
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doi:10.1097/MAJ.0b013e31824369c5 54

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All referenced studies are pre-clinical and exploratory
