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2.2 GPX2 Glutathione peroxidase 2 (GPX2) is mainly expressed in the gastrointestinal system, including the intestinal epithelium, esophageal epithelial cells, etc., and can also be detected in the human liver (Esworthy et al., 2022)
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Thus, cells with PIK3CA mutations exhibit increased sensitivity to glutamine deprivation
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