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CrossRef Association between phenols and thyroid hormones: The role of iodothyronine deiodinase genes Blanca Sarzo, Reem Abumallouh, Natalia Marn, Sabrina Llop, Andrea Beneito, Inmaculada Lopez-Flores, Nerea Ferrero, Amrit Kaur Sakhi, Ferran Ballester, Maria-Jose Lopez-Espinosa Environmental Pollution.2022

It can help brighten the complexion, reduce pigmentation, and improve skin elasticity by combating oxidative stress and supporting cellular regeneration

For HIF transcription factors, this occurs by hydroxylation at conserved proline residues by prolyl hydroxylases under normoxia, allowing their recognition and ubiquitination by the VHL E3 ubiquitin ligase, which targets HIFs for proteasomal degradation
At the center of this effort is a molecule often called the master antioxidant: glutathione
