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Mechanistic studies reveal that ferroptotic cells release substantial quantities of HMGB1 and ATP, resulting in a 4.7-fold increase in DC activation and 3.2-fold enhancement in T-cell priming efficiency [168]

Kanti V, Messenger A, Dobos G, Reygagne P, Finner A, Blumeyer A, Trakatelli M, Tosti A, Del Marmol V, Piraccini BM, Nast A, Blume-Peytavi U

Specifically, inflammatory bowel disease is a risk factor for colitis-associated colorectal cancer (CAC) development, highlighting the connection between chronic inflammation and tumorigenesis [4]

This has been demonstrated to inhibit the proliferation and metastasis of thyroid cancer and to enhance the innate immune response [143]