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Description
They tested these inhibitors in cell and animal models. They reported changes in intracellular nicotinamide-related metabolites and examined the biological effects of NNMT inhibition under experimental conditions. These outcomes have increased scientific interest in NNMT biology

Sirtuin control of mitochondrial dysfunction, oxidative stress, and inflammation in chagas disease models
Nakamura, E
Neuroinflammatory processes are a central feature in the development of degenerative disease
