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Further work utilizing whole-cell fluorescence-based library assays also revealed a reduced specificity at the P6 position where glutamic acid was originally suggested to be strongly favored [4]

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doi: 10.3389/fbioe.2025.1582189 Received 24 February 2025 Accepted 30 June 2025 Published 14 July 2025 Volume 13 - 2025 Edited by Chun Zeng, Third Affiliated Hospital, Southern Medical University, China Reviewed by Sacha Cavelier, Queensland University of Technology, Australia Ankita Samanta, University of British Columbia, Canada Updates Copyright 2025 Nie, Liu, Zeng, Hu, Wang, Huang, Chen, Hu and Xu