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Subunit-specific organization of NMDARs within spine synapses The synaptic content of GluN2A and GluN2B NMDAR subunits changes the ability of a synapse to undergo structural plasticity, suggesting that the specific ratio of GluN2A to GluN2B in NMDAR heterotetramers may tune synaptic function 1,9,10

[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Zhang J, Motyl KJ, Irwin R, MacDougald OA, Britton RA, McCabe LR

What these compounds share is not a mechanism or a therapeutic category
