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Additionally, although Phase 1 studies were not primarily efficacy trials, they did record early signs of weight loss and reduced appetite in participants receiving the higher doses of cagrilintide (especially in combination with semaglutide), hinting at the powerful effect to be quantified in subsequent trials

While considered safe, they should only be administered under proper medical supervision, with attention to individual health factors and existing conditions [3]

[40], ADRA [44], Sun & Conejo [45], Ospina et al

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