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A double-blind, placebo-controlled trial could be helpful in exploring these questions (of note, the authors of this paper are currently conducting a clinical trial with secondary and exploratory outcomes aimed to explore symptomatic benefits, NCT04584346)

Response to Reviewers A transcript of the reviewer comments and author responses from the Live Peer Review Jamboree can be found here: Taipei American School Response to Reviewers References World Health Organization

Nrf2 also promotes the production of heme oxygenase-1 (HO-1) to protect hepatocytes from oxidative stress, and HO-1 attenuates alcohol-induced liver damage by suppressing inflammatory responses [11]

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