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In another study, gastrocnemius muscle BCAT2 protein level is not different between lean and obese Zucker rats, irrespective of their nutritional status (She et al., 2007b)

Results MSG significantly increased the serum level of MDA, BUN, creatinine, uric acid and renal Caspase-9, NGAL and KIM-1 expression, but it decreased the serum activity also renal expression of SOD, catalase, GPX, and Bcl-2 expression compared to the control group

Phospho-protein kinase B (phospho-AKT) (Cat #9271), phospho-ribosomal protein S6 (phopho-RPS6K1) (Cat# #2215), and Glycerinaldehyde-3-phosphate-Dehydrogenase (GAPDH) (Cat #4691) were purchased from Cell Signaling Technologies (Danvers, MA, USA)

Every dogs metabolism is different, and like humans it can come down to genetics, nutrition, age, and diet
