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[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Finkelstein J.D., Kyle W.E., Harris B.J

As primordial germ cells ( PGCs ) of the developing embryo enter the genital ridge, genome-wide demethylation occurs which erases the imprint marks (solid grey lines) present on the maternal and paternal chromosomes ( DNA demethylation ), and de novo methylation follows to establish the new sex-specific imprints during gametogenesis ( sex-specific remethylation )

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10.1038/s41598-018-19213-4 185 SatoR.NakanoT.HosonagaM.SampetreanO.HarigaiR.SasakiT.et al (2017)
