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Description
The cannabinoid-mediated reduction in neurotransmitter release is achieved by the reduced influx of presynaptic Ca 2+ due to the inhibition of voltage gated Ca 2+ channels and of adenylyl cyclase, which downregulates cyclic adenosine monophosphate and protein kinase A, two cellular constituents involved in increasing the influx of Ca 2+ (Castillo et al., 2012)
& Schock, H
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Journal of Physiology and Pharmacology: an Official Journal of the Polish Physiological Society, 60(Suppl 7), 191196
