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The area under the ROC curve was 0.953% and the 95% confidence interval was 0.8721 for the eight identified metabolites that were included in a model predictor (Fig

It belongs to the CD33-related Siglec family which contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail and recognize sialic acids on host cells as self-associated molecular patterns (SAMPs) to dampen innate immune responses (177, 178)