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E.TsaftarisA.et al (2015)

5.1 Metabolic auxotrophy as an attenuation strategy Metabolic auxotrophy is a classic attenuation approach in which one or more critical genes in vital metabolite biosynthetic pathways are deleted, thereby causing the bacterial cell to rely on an exogenous supply of the targeted metabolite

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J Invest Dermatol 129:21672174 van Diepen JA, Jansen PA, Ballak DB, Hijmans A, Hooiveld GJ, Rommelaere S, Galland F, Naquet P, Rutjes FP, Mensink RP, Schrauwen P, Tack CJ, Netea MG, Kersten S, Schalkwijk J, Stienstra R (2014) PPAR dependent regulation of vanin-1 mediates hepatic lipid metabolism
