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Brain 10:22

We also explore cholesterol-induced alterations in BAs metabolism, gut microbiota composition, and the LAAMP pathway

DHODH holds a pivotal position in the biosynthetic pathway of pyrimidine nucleotides, playing a crucial role in the production of DNA and RNA (49), Inhibition of DHODH disrupts this pathway, leading to abnormalities in, or cessation of, pyrimidine nucleotide synthesis