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Although the overall number (frequency) of Tregs may be unchanged in MS patients compared to controls, studies indicate that their inhibitory function is impaired, which correlates with diminished immune control in vivo (Costantino et al., 2008)

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Dies wird bei chronischer Mdigkeit und Erschpfung, chronischen Infekten, Autoimmunerkrankungen oder in der komplementren Krebstherapie getan

6.3.3 Trial-design lessons Future trials should: enrich for participants with high redox/ferroptosis burden (biomarker-enriched enrollment)