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The small studies on knee pain and bladder pain are interesting, but they involved fewer than 30 patients total

Although vitamin B 12 deficiency is known to damage the myelin sheath covering cranial, spinal, and peripheral nerves, the biochemical processes leading to neurologic damage in vitamin B 12 deficiency are not yet fully understood (22)

doi: 10.1159/000192434

The rationale for combining these two peptides is rooted in their complementary mechanisms of action
