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These are considered an alternative treatment to metformin, as their function lies in the modulation of the components that signal the insulin pathways, thus influencing processes such as the regulation of the menstrual cycle, carbohydrate metabolism, and hyperandrogenism

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The role of choline in betaine synthesis, and the subsequent principal role of betaine as a methyl donor primarily in the context of the methionine cycle in the liver, makes this function of choline one of its most important