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Fluorescence changes were expressed as percentage changes from baseline (% R/R)
SCFAs like butyrate, which are generated through probiotic fermentation of dietary fiber, inhibit HDACs, leading to epigenetic silencing of pro-inflammatory cytokines (e.g., IL-1, TNF-) by downregulating NF-B and upregulating IL-10 by activating STAT3 (98, 102, 103)
V., Tseng, R
GSH brain concentrations are not commonly measured using 1 H-MRS, because relative to other 1 H-MRS-detectable neurochemicals (e.g., creatine (Cr), choline, N -acetylasparate), GSH concentrations are substantially lower
