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Description
In addition, the absence or decrease in levels of cytosolic GSH resulted in PDI becoming more oxidized, limiting the ability of the enzyme to isomerize nonnative disulphide bonds

PMID 16192629

Perico N

At the moment that the GH dose was decreased or increased the GH-deficient patients in the present study were already treated with GH for more than 1 year (and IGF-1 levels being between 1 and 1 SDS for at least 6 months)
