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Following a detailed consultation with Dr

If we accept the context dependency of microbial-mediated IR is inevitable, we need to focus on developing environmentally stable commercial formulations and compositions of secondary metabolites of beneficial microbes that are known to trigger the resistance in laboratory conditions, as they may induce resistance consistently under field conditions as well

Liu L-H, Qiu W-X, Li B, et al

11 However, the clinical significance of crossing the line in this fashion is unknown
